Flex Pharma Educates Athletes about Breakthrough Discovery

Flex Pharma, Inc. (NASDAQ: FLKS), a company developing innovative and proprietary treatments for exercise-associated muscle cramps, nocturnal leg cramps, and spasms associated with severe neuromuscular conditions, has launched a print and digital campaign with the objective to build awareness and educate consumers that the root cause of muscle cramping is the nerve, not the muscle. To date, the Company’s findings and its development of the first scientifically proven formula to treat and prevent muscle cramps have appeared in Outside Magazine, Competitor, Runner’s World, Bicycling, and Running Times, among others.  “The excitement around this scientific breakthrough is remarkable. People in the endurance community and beyond are fascinated and encouraged by the genius discovery from Nobel Prize-winner and company founder, Dr. Rod MacKinnon," said Marina Hahn, President Consumer. “We know how painful cramping can be to those with an active lifestyle, and will continue to partner with influential media to spread the news of our scientific discovery throughout the year.”   Flex Pharma’s educational effort and awareness campaign around athletes participating in high intensity sports has included participation in a variety of endurance events, including IRONMAN Boulder, Leadville Trail 100 MTB and Leadville Trail 100 Run. The Company also will appear at the IRONMAN World Championships presented by GoPro and IRONMAN Sports Medicine Conference in October prior to a consumer product being available to the public in 2016.   The goal of Flex Pharma’s efforts is to take athletes beyond the traditional mindset that exercise-associated muscle cramps are caused by a problem with the muscle. Instead, the Company is highlighting the real culprit: the nerve. No matter what conditions impact muscle performance in the first place – heat, fatigue, dehydration, electrolyte loss, reduced blood flow – the cramping of a muscle is triggered by the excessive firing of motor neurons in the spinal cord. The muscle then bunches up and is unable to relax, resulting in loss of motor control and pain. Drawing on his Nobel Prize winning research, Dr. MacKinnon designed a sports beverage to stimulate sensory fibers and prevent the motor nerves from becoming hyper-excited, greatly reducing the risk of cramping. This novel mechanism of chemical neurostimulation is leading to a new category in nutrition: Neuromuscular Performance – a focus on creating and sustaining the right nervous system conditions in the body for optimal neuromuscular balance.    About Flex Pharma Flex Pharma, Inc. is a biotechnology company that is developing innovative and proprietary treatments for exercise-associated muscle cramps, nocturnal leg cramps, and spasms associated with severe neuromuscular conditions. In three randomized, blinded, placebo-controlled, cross-over studies, Flex Pharma's proprietary treatment has shown a statistically significant reduction in the intensity of muscle cramps in healthy normal volunteers.   Flex Pharma was founded by National Academy of Sciences members Rod MacKinnon, M.D. (2003 Nobel Laureate), and Bruce Bean, Ph.D., recognized leaders in the fields of ion channels and neurobiology, along with Chairman and Chief Executive Officer Christoph Westphal, M.D., Ph.D.   Individuals can follow the Company on Twitter (@flexpharma) and the Company's website (http://ir.flex-pharma.com/) to see the latest progress of the Company's pre-launch activities for its consumer product to prevent and treat exercise-associated muscle cramps.

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